Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280399 | 0.87 | PTPN11 (0.50) | PTPN11L3MBTL1MAPTALDH1A1ENPP3 | |
| SCHEMBL31396642 | 0.86 | PTPN11 (0.53) | PTPN11GCKL3MBTL1MAPTALDH1A1 | |
| SCHEMBL31396616 | 0.85 | PTPN11 (0.53) | PTPN11L3MBTL1GAAMAPTALDH1A1 | |
| SCHEMBL31396576 | 0.85 | PTPN11 (0.49) | PTPN11L3MBTL1MAPTALDH1A1ENPP3 | |
| SCHEMBL31344454 | 0.81 | PTPN11 (0.50) | PTPN11L3MBTL1MAPTALDH1A1ENPP3 | |
| SCHEMBL1516664 | 0.80 | PTPN11 (0.52) | PTPN11L3MBTL1MAPTALDH1A1ENPP3 | |
| SCHEMBL720190 | 0.80 | PTPN11 (0.49) | PTPN11L3MBTL1MAPTALDH1A1ENPP3 | |
| SCHEMBL31396553 | 0.80 | PTPN11 (0.54) | PTPN11L3MBTL1GAAMAPTALDH1A1 | |
| SCHEMBL31396517 | 0.80 | PTPN11 (0.49) | PTPN11L3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL23247251 | 0.80 | L3MBTL1 (0.58) | PTPN11L3MBTL1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425499-A1 | TYRO3 INHIBITORS | HALIA THERAPEUTICS INC (US) | 2024-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425499-A1 | TYRO3 INHIBITORS | TYRO3, TYR, TH | PTPN11 80/4885GCK 2595/4885L3MBTL1 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.