Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.49 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31397927 | 0.87 | NPC1 (0.42) | TYK2JAK1JAK2NPC1RAB9A | |
| SCHEMBL31397976 | 0.78 | IRAK4 (0.54) | TYK2JAK1JAK2NPC1RAB9A | |
| SCHEMBL31397929 | 0.78 | SMN1; SMN2 (0.45) | JAK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31397951 | 0.78 | TYK2 (0.50) | TYK2JAK1JAK2CYP3A4NPC1 | |
| SCHEMBL31398130 | 0.78 | NPC1 (0.53) | TYK2JAK1JAK2CYP3A4NPC1 | |
| SCHEMBL29789055 | 0.78 | TYK2 (0.61) | TYK2JAK1STAT3JAK2CYP3A4 | |
| SCHEMBL31397946 | 0.75 | JAK2 (0.53) | TYK2JAK1JAK2 | |
| SCHEMBL31397954 | 0.75 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31397965 | 0.72 | IRAK4 (0.45) | TYK2JAK1JAK2NPC1RAB9A | |
| SCHEMBL31397930 | 0.70 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024262911-A1 | NOVEL PYRAZOLO PYRIMIDINE-BASED COMPOUND AND USE THEREOF | 주식회사 에이조스바이오 | 2024-12-26 | — | — | WO | claimed |
| WO-2024262911-A1 | NOVEL PYRAZOLO PYRIMIDINE-BASED COMPOUND AND USE THEREOF | 주식회사 에이조스바이오 | 2024-12-26 | — | — | WO | disclosed |