Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398170 | 0.84 | TGFBR1 (0.43) | TGFBR1RAB9ANPC1 | |
| SCHEMBL20199807 | 0.82 | JAK2 (0.44) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30864203 | 0.78 | KDM4E (0.55) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10204204 | 0.76 | PDE2A (0.53) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30864198 | 0.76 | HPGD (0.67) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30864194 | 0.76 | MAPT (0.61) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL312787 | 0.76 | TGFBR1 (0.55) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL17781064 | 0.76 | TGFBR1 (0.57) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL461752 | 0.75 | TGFBR1 (0.51) | TGFBR1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL16718855 | 0.75 | KDM4E (0.58) | TGFBR1KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024262911-A1 | NOVEL PYRAZOLO PYRIMIDINE-BASED COMPOUND AND USE THEREOF | 주식회사 에이조스바이오 | 2024-12-26 | — | — | WO | disclosed |