⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870932 | 0.85 | GRM5 (0.59) | — | |
| SCHEMBL31286309 | 0.85 | GRM5 (0.59) | — | |
| SCHEMBL27790282 | 0.76 | — | — | |
| SCHEMBL29994137 | 0.76 | — | — | |
| SCHEMBL16115141 | 0.76 | — | — | |
| SCHEMBL28806725 | 0.76 | — | — | |
| SCHEMBL15870983 | 0.76 | — | — | |
| SCHEMBL4637898 | 0.73 | GRM5 (0.49) | — | |
| SCHEMBL23497950 | 0.71 | GRM5 (0.47) | — | |
| SCHEMBL22548043 | 0.71 | GRM5 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025039676-A1 | PAN-KRAS PROTEIN TARGETED DEGRADER COMPOUND AND USE THEREOF | 贝达药业股份有限公司 | 2025-02-27 | — | — | WO | disclosed |