Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870932 | 0.81 | GRM5 (0.59) | GRM5HSP90AA1HAO1KDM4ENAPRT | |
| SCHEMBL31286309 | 0.81 | GRM5 (0.59) | GRM5HSP90AA1HAO1KDM4ENAPRT | |
| SCHEMBL30206276 | 0.78 | GRM5 (0.45) | GRM5HSP90AA1KDM4E | |
| SCHEMBL29994137 | 0.77 | — | — | |
| SCHEMBL15870983 | 0.77 | — | — | |
| SCHEMBL22548041 | 0.76 | GRM5 (0.41) | GRM5HAO1 | |
| SCHEMBL31398425 | 0.73 | — | — | |
| SCHEMBL28806725 | 0.73 | — | — | |
| SCHEMBL16115141 | 0.73 | — | — | |
| SCHEMBL27790282 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941132-B2 | Pyrazole derivatives | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2021-03-09 | — | — | US | disclosed |
| CN-110194770-A | Peptide acyl arginine deiminase inhibitor and application thereof | 南京药捷安康生物科技有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-110117285-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |
| US-20190002432-A1 | PYRAZOLE DERIVATIVES | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2019-01-03 | — | — | US | disclosed |
| CN-109053742-A | New tricyclic compound | ABBVIE 公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108774237-A | New tricyclic compound | ABBVIE 公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-108727369-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-104370909-B | Tricyclic compound | ABBVIE 公司 | 2018-09-11 | — | — | CN | disclosed |
| CN-104884059-B | Mixing pedigree kinase inhibitor for HIV/AIDS treatments | 罗切斯特大学 | 2018-08-10 | — | — | CN | disclosed |
| CN-108218873-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2018-06-29 | — | — | CN | disclosed |
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1217001-B1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | EISAI CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
| EP-1214303-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016121-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | MERCK & CO., INC. (US) | 2001-03-08 | — | — | WO | disclosed |
| US-5639753-A | CONTROLLING INSECTS IN AGRICULTURE CROPS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5532367-A | LARVICIDES | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5521190-A | USEFUL AGAINST TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1994027439-A1 | INSECTICIDAL PTERIDINES AND 8-DEAZAPTERIDINES | FMC CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941132-B2 | Pyrazole derivatives | GRM5, GRIK5, GRIN2C | GRM5 1/4885HSP90AA1 2413/4885HAO1 4141/4885 |
| US-20190002432-A1 | PYRAZOLE DERIVATIVES | GRM5, GRIK5, GRIN2C | GRM5 1/4885HSP90AA1 2413/4885HAO1 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.