Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159371 | 0.85 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| SCHEMBL12740946 | 0.85 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| SCHEMBL18152220 | 0.85 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| SCHEMBL5473688 | 0.85 | HTR2C (0.47) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| SCHEMBL18159372 | 0.85 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL18149706 | 0.84 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL1448748 | 0.84 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL18149704 | 0.84 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL18149815 | 0.84 | ROCK2 (0.42) | ROCK2ROCK1HTR2CHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL31045885 | 0.84 | HTR2C (0.47) | ROCK2ROCK1HTR2CHTR2BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040167-A1 | PHOSPHOINOSITIDE 3-KINASE ALLOSTERIC INHIBITOR FOR TREATING DISEASE RELATED TO PI3K REGULATION | 上海艾力斯医药科技股份有限公司 | 2025-02-27 | — | — | WO | disclosed |