SCHEMBL31400283

SCHEMBL31400283

Fc1c(F)c(F)c(-c2cc(-c3ccccn3)cc(-c3ccccn3)c2)c(F)c1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.48
CCR1 P32246 3/20 0.48
CCR5 P51681 3/20 0.48
CCR8 P51685 3/20 0.48
LMNA P02545 3/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.48
METAP1 P53582 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
CYP2A6 P11509 1/20 0.44
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
TP53 P04637 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALOX15 P16050 2/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21988535 1.00 KDM4E (0.48) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL12957449 0.89 CYP2A6 (0.46) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL12405055 0.86 KDM4E (0.50) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL4140079 0.83 KDM4E (0.62) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL31568869 0.83 KDM4E (0.62) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL16672906 0.83 KDM4E (0.68) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL5945969 0.82 GRM5 (0.56) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL14426234 0.81 KDM4E (0.65) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL23843485 0.81 CCR1 (0.50) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL5845764 0.80 KDM4E (0.52) KDM4ECCR1CCR5CCR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775323-A Transition metal luminescent complexes and methods of use 香港大学 2025-04-08 CN disclosed
CN-111269711-B Transition metal luminescent complexes and methods of use 香港大学 2025-02-25 CN disclosed