SCHEMBL5845764

SCHEMBL5845764

Fc1cc(-c2ccccn2)cc(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.52
LMNA P02545 3/20 0.52
CCR1 P32246 3/20 0.52
CCR5 P51681 3/20 0.52
CCR8 P51685 3/20 0.52
METAP1 P53582 2/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
BLM P54132 1/20 0.52
HIF1A Q16665 1/20 0.52
DOHH Q9BU89 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
CBFB Q13951 3/20 0.49
RAB9A P51151 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP2A6 P11509 1/20 0.47
TP53 P04637 3/20 0.45
NPC1 O15118 3/20 0.45
TDP1 Q9NUW8 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16672906 0.82 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
SCHEMBL160064 0.82 KDM4E (0.67) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27980340 0.81 KDM4E (0.45) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5846133 0.81 GRM5 (0.60) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28180497 0.81 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5945969 0.81 GRM5 (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL13799201 0.80 KDM4E (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21988535 0.80 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL31400283 0.80 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8
SCHEMBL14426234 0.80 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103450283-B One class complex of iridium and method for making thereof and the application at organic electroluminescence device NANJING UNIVERSITY (CN) 2015-10-14 CN disclosed
CN-103450283-A Novel iridium complex and preparation method thereof as well as application thereof in organic electroluminescence device NANJING UNIVERSITY OF TECHNOLOGY 2013-12-18 CN disclosed
CN-1325503-C Luminous organic intermetallic compound and luminous element SANYO ELECTRIC CO (JP) 2007-07-11 CN disclosed
US-7067202-B2 Luminous efficiency and capable of emitting light of spectrum components of red or blue wavelength band; for use in organic electroluminescent device SANYO ELECTRIC CO., LTD. (JP) 2006-06-27 US disclosed
US-20030040627-A1 Luminescent organometallic compound and light emitting device SANYO ELECTRIC CO., LTD. (JP) 2003-02-27 US disclosed
CN-1397559-A Luminous organic intermetallic compound and luminous element SANYO ELECTRIC CO (JP) 2003-02-19 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030040627-A1 Luminescent organometallic compound and light emitting device IK, CRY1, LBR KDM4E 3641/4885LMNA 3413/4885CCR1 1165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.