SCHEMBL314018

SCHEMBL314018

CC(C)C(=O)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6404922 0.97
Methylene Chloride SCHEMBL28623150 0.91 TRPA1 (0.38)
SCHEMBL9792803 0.78
SCHEMBL13559062 0.78
SCHEMBL24074651 0.77 CYP1A2 (0.38)
SCHEMBL20078924 0.75
SCHEMBL4263880 0.75
SCHEMBL6404918 0.75
SCHEMBL6577704 0.73
SCHEMBL8407864 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1030 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107377-A1 PHARMACOLOGICAL RE-ACTIVATION OF MUTANT PVHL KARANICOLAS JOHN (US) 2026-05-21 WO disclosed
US-20260125359-A1 HETEROARYL COMPOUNDS AS MULTI-TARGET PROTEIN KINASE INHIBITORS FUJIAN HAIXI PHARMACEUTICALS CO LTD (CN) 2026-05-07 US disclosed
US-12617785-B2 Pyrrolo[2,3-b]pyridine-3-carboxamide compositions and methods for ameliorating hearing loss THE ROCKEFELLER UNIVERSITY (US) 2026-05-05 US disclosed
EP-4711368-A1 AZEPINE COMPOUND, AND COMPOSITION AND USE THEREOF CHENGDU MFS PHARMA. CO., LTD. (CN) 2026-03-18 EP disclosed
US-20260048045-A1 PI3K-ALPHA INHIBITORS FOR THE TREATMENT OF CANCER SCORPION THERAPEUTICS INC (US) 2026-02-19 US disclosed
EP-4334298-B1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS INC (US) 2026-02-18 EP disclosed
US-20260041672-A1 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators, Pharmaceutical Compositions, and Uses Thereof UNIV EMORY (US) 2026-02-12 US disclosed
CN-121226193-A Trifluoro-methoxy method for synthesizing wei 江苏海洋大学 2025-12-30 CN disclosed
US-12503477-B2 Colony stimulating factor-1 receptor (CSF-1R) inhibitors GENZYME CORPORATION 2025-12-23 US disclosed
US-12473295-B2 Substituted straight chain spiro derivatives JANSSEN PHARMACEUTICA NV (BE) 2025-11-18 US disclosed
US-4584373-A MICROBIOCIDES, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1986-04-22 US disclosed
US-4535081-A Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor PFIZER INC. (US) 1985-08-13 US disclosed
US-4514566-A INSECTICIDES, MOLLUSCICIDES, MITICIDES AND NEMATOCIDES HOFFMANN-LA ROCHE INC. (US) 1985-04-30 US disclosed
EP-0131867-A2 Aryloxy-pyrimidinyl alkanols BAYER AG (DE) 1985-01-23 EP disclosed
US-4427687-A INSECTICIDES, MITICIDES, AND MOLLUSCICIDES HOFFMANN-LA ROCHE INC. (US) 1984-01-24 US disclosed
US-4423048-A Antiallergic and antiulcer 1-oxo-1H-thiazolo[3,2-a]pyrimidine-2-carboxamides and intermediates therefor PFIZER INC. (US) 1983-12-27 US disclosed
US-4414388-A ANTIALLERGENS, ANTIULCER AGENTS PFIZER INC. (US) 1983-11-08 US disclosed
US-4321372-A Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides PFIZER INC. (US) 1982-03-23 US disclosed
EP-0039520-A1 Carbamoyl oximes, processes and intermediates for their preparation, pesticides containing them and use of these compounds as pesticides F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-11-11 EP disclosed
US-4240983-A HALOGENATION BAYER AKTIENGESELLSCHAFT (DE) 1980-12-23 US disclosed