Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.76 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.72 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | F2R | P25116 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501632 | 0.98 | HPGD (0.79) | HPGDKCNK3KCNK9NPSR1F2R | |
| SCHEMBL31401955 | 0.94 | MAPT (0.68) | HPGDKCNK3KCNK9NPSR1ALDH1A1 | |
| SCHEMBL31401950 | 0.92 | HPGD (0.83) | HPGDKCNK3KCNK9NPSR1SMN1; SMN2 | |
| SCHEMBL19501631 | 0.90 | HPGD (0.87) | HPGDKCNK3KCNK9ALDH1A1SMN1; SMN2 | |
| SCHEMBL4668488 | 0.88 | HPGD (0.96) | HPGDKCNK3KCNK9NPSR1ALDH1A1 | |
| SCHEMBL1300190 | 0.87 | HPGD (1.00) | HPGDKCNK3KCNK9NPSR1ALDH1A1 | |
| SCHEMBL19703413 | 0.87 | HPGD (1.00) | HPGDKCNK3KCNK9NPSR1ALDH1A1 | |
| SCHEMBL2184247 | 0.85 | HPGD (0.89) | HPGDKCNK3KCNK9NPSR1ALDH1A1 | |
| SCHEMBL19501808 | 0.83 | HPGD (0.73) | HPGDKCNK3KCNK9NPSR1ALDH1A1 | |
| SCHEMBL11863584 | 0.81 | GAA (0.68) | HPGDKCNK3KCNK9NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228630-B1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2025-03-05 | — | — | EP | claimed |
| EP-4228630-B1 | NLRP3 ACTIVATORS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES OR CANCER BY ACTIVATING NLRP3 INFLAMMASOME | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2025-03-05 | — | — | EP | disclosed |