SCHEMBL31403153

SCHEMBL31403153

Cc1c[nH]c(=O)nc1N.[Sn]

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.35
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22008 0.98
SCHEMBL1231792 0.98 ATAD2 (0.37) ATAD2CYP1A2
SCHEMBL30609151 0.98
Hydrochloric Acid SCHEMBL2199283 0.96 ATAD2 (0.35) ATAD2CYP1A2
Water SCHEMBL28196064 0.96 ATAD2 (0.35) ATAD2CYP1A2
SCHEMBL30917957 0.96 ATAD2 (0.35) ATAD2CYP1A2
SCHEMBL15571194 0.88 ATAD2 (0.31) ATAD2
Phosphoric Acid SCHEMBL17185718 0.88 ADORA2A (0.32) ATAD2CYP1A2
Phosphoric Acid SCHEMBL7587250 0.88 ADORA2A (0.32) ATAD2CYP1A2
Sulfuric Acid SCHEMBL28173989 0.88 ATAD2 (0.31) ATAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976791-B1 COMPOUNDS AND METHODS FOR REDUCING FUS EXPRESSION IONIS PHARMACEUTICALS INC (US) 2025-04-09 EP claimed