Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 4/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18042582 | 1.00 | PARP1 (0.45) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL18057557 | 0.91 | KDM4E (0.45) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL30287945 | 0.91 | KDM4E (0.47) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL17254907 | 0.91 | KDM4E (0.47) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL18042590 | 0.90 | KDM4E (0.47) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL17254979 | 0.90 | ALDH1A1 (0.44) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL18042591 | 0.89 | KDM4E (0.43) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL30287931 | 0.89 | KDM4E (0.43) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL30168034 | 0.89 | KDM4E (0.43) | PARP1KDM4EALDH1A1HTR3AHRH4 | |
| SCHEMBL17255052 | 0.89 | ALDH1A1 (0.43) | PARP1KDM4EALDH1A1HTR3AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3219716-B1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | PIMERA INC (US) | 2024-12-25 | — | — | EP | disclosed |