SCHEMBL31404151

SCHEMBL31404151

O=C(O)[C@@H]1Cc2ccc(-c3ccccn3)cc2C1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FAAH O00519 14/20 0.58
DHODH Q02127 1/20 0.46
ABL1 P00519 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31404170 1.00 FAAH (0.58) FAAHDHODHABL1
SCHEMBL30664942 1.00 FAAH (0.58) FAAHDHODHABL1
SCHEMBL21557425 1.00 FAAH (0.58) FAAHDHODHABL1
SCHEMBL26656354 1.00 FAAH (0.58) FAAHDHODHABL1
SCHEMBL26656409 1.00 FAAH (0.58) FAAHDHODHABL1
SCHEMBL21557586 0.89 FAAH (0.55) FAAHABL1
SCHEMBL21557578 0.84 FAAH (0.54) FAAHABL1
SCHEMBL26818703 0.82 FAAH (0.49) FAAHDHODHABL1
SCHEMBL21557666 0.82 CYP4F2 (0.47) FAAHDHODHABL1
SCHEMBL16595696 0.81 FAAH (0.48) FAAHDHODHABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025104687-A1 SOLID FORMS OF A HSV HELICASE PRIMASE INHIBITOR GILEAD SCIENCES, INC. (US) 2025-05-22 WO disclosed
CN-119546574-A Antiviral indolinyl compounds and uses thereof 吉利德科学公司 2025-02-28 CN disclosed