Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9580413 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL150827 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL29055889 | 0.91 | TSHR (0.36) | TSHR | |
| Hydrochloric Acid SCHEMBL9720529 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL28429555 | 0.87 | — | — | |
| Fluoride Ion SCHEMBL1538604 | 0.82 | — | — | |
| Bromide SCHEMBL1539068 | 0.82 | — | — | |
| SCHEMBL146307 | 0.82 | — | — | |
| SCHEMBL312064 | 0.82 | — | — | |
| Iodide SCHEMBL1686767 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206734-A1 | Low molecular weight high-cis polybutadienes | Bridgestone Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |
| EP-1189983-B1 | LOW MOLECULAR WEIGHT HIGH-CIS POLYBUTADIENES | BRIDGESTONE CORP (JP) | 2010-04-21 | — | — | EP | disclosed |
| US-6437205-B1 | USING NEODYMIUM CARBOXYLATE, ALUMINOXANE, AND TRIALKYL ALUMINUM CATALYST SYSTEM; GOOD WET TRACTION AND ROLLING RESISTANCE; GOOD PHYSICAL PROPERTIES | BRIDGESTONE CORPORATION (JP) | 2002-08-20 | — | — | US | disclosed |
| EP-1189983-A2 | LOW MOLECULAR WEIGHT HIGH-CIS POLYBUTADIENES | Bridgestone Corporation (JP) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000069928-A2 | LOW MOLECULAR WEIGHT HIGH-CIS POLYBUTADIENES | BRIDGESTONE CORPORATION (JP) | 2000-11-23 | — | — | WO | disclosed |