Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.42 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396475 | 0.86 | SMN1; SMN2 (0.65) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL22912831 | 0.86 | SMN1; SMN2 (0.65) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL29220893 | 0.83 | USP30 (0.49) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL25738320 | 0.82 | PARP1 (0.47) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL27203534 | 0.82 | SMN1; SMN2 (0.60) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL27203569 | 0.81 | MEN1 (0.48) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL31048020 | 0.80 | MEN1 (0.45) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL25738115 | 0.80 | HDAC1 (0.48) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL25208908 | 0.79 | HRH3 (0.71) | MEN1MAPTTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL25293821 | 0.79 | USP30 (0.50) | MEN1MAPTTSHRKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025073583-A1 | PARP1 INHIBITOR COMPOUNDS | Duke Street Bio Limited (GB) | 2025-04-10 | — | — | WO | disclosed |