Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220928 | 0.92 | USP30 (0.43) | USP30DDB1CRBNGPR119CCNT1 | |
| SCHEMBL25093627 | 0.87 | DDB1 (0.58) | USP30DDB1CRBNGPR119WNT3A | |
| SCHEMBL29220941 | 0.86 | USP30 (0.46) | USP30DDB1CRBNGPR119WNT3A | |
| SCHEMBL31404580 | 0.83 | MEN1 (0.50) | USP30GPR119MEN1MAPTTSHR | |
| SCHEMBL31598717 | 0.80 | USP30 (0.52) | USP30DDB1CRBNGPR119WNT3A | |
| SCHEMBL30902535 | 0.79 | USP30 (0.51) | USP30GPR119 | |
| SCHEMBL25286886 | 0.79 | USP30 (0.51) | USP30GPR119 | |
| SCHEMBL30896212 | 0.79 | USP30 (0.51) | USP30GPR119 | |
| SCHEMBL25243822 | 0.79 | USP30 (0.51) | USP30GPR119 | |
| SCHEMBL31362194 | 0.79 | USP30 (0.51) | USP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119629-A | Nitrogen-containing heterocyclic compound and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-31 | — | — | CN | disclosed |