Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22349711 | 0.87 | MAPT (0.39) | MAPT | |
| SCHEMBL18084817 | 0.86 | MAPT (0.35) | MAPT | |
| SCHEMBL20911099 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL25311167 | 0.84 | MAPT (0.31) | MAPT | |
| SCHEMBL17472486 | 0.80 | MAPT (0.36) | MAPT | |
| SCHEMBL18019792 | 0.80 | MAPT (0.36) | MAPT | |
| SCHEMBL18065630 | 0.76 | MAPT (0.40) | MAPT | |
| SCHEMBL321458 | 0.75 | — | — | |
| SCHEMBL7847424 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL62939 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034167-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2025-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034167-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | KRAS, NRAS, HRAS | MAPT 4648/4885HTR2A 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.