Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17472486 | 1.00 | MAPT (0.36) | MAPTOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL20911099 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL25311167 | 0.86 | MAPT (0.31) | MAPT | |
| SCHEMBL7796963 | 0.86 | OPRM1 (0.39) | MAPTOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL22349711 | 0.85 | MAPT (0.39) | MAPTTSHR | |
| SCHEMBL14532454 | 0.81 | OPRM1 (0.33) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL31404666 | 0.80 | MAPT (0.33) | MAPT | |
| SCHEMBL16927480 | 0.79 | MAPT (0.35) | MAPTOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL11219918 | 0.74 | SLC6A2 (0.38) | MAPTTSHR | |
| SCHEMBL3052069 | 0.74 | MAPT (0.33) | MAPTOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128140-A1 | PYRIMIDINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | WO | disclosed |