Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | MYC | P01106 | 4/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871992 | 0.81 | TDP1 (0.59) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL7031169 | 0.81 | MYC (0.59) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL20264529 | 0.79 | MAPT (0.51) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL1813710 | 0.77 | MAPT (0.49) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL30619374 | 0.76 | MAPT (0.49) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL28398442 | 0.76 | MAPT (0.49) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL23245567 | 0.76 | CTSB (0.54) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL31329466 | 0.76 | CTSB (0.54) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL12180526 | 0.75 | MYC (0.58) | TDP1CTSBMYCNR4A1MAPT | |
| SCHEMBL8387974 | 0.74 | MAPT (0.47) | MYCNR4A1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054369-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | NICO THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |