SCHEMBL31406535

SCHEMBL31406535

O=C(O)c1ccc(O)cc1OCCOCc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
KMT2A Q03164 2/20 0.56
PTK2B Q14289 1/20 0.56
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
MCL1 Q07820 3/20 0.50
MAOB P27338 1/20 0.46
FOLH1 Q04609 1/20 0.45
ADRB3 P13945 1/20 0.43
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTGS2 P35354 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583147 0.86 MCL1 (0.63) ALDH1A1KMT2AESR1ESR2MCL1
SCHEMBL31406542 0.86 ALDH1A1 (0.53) ALDH1A1KMT2APTK2BMCL1MAOB
SCHEMBL10937668 0.84 ALDH1A1 (0.69) ALDH1A1KMT2APTK2BESR1ESR2
SCHEMBL21924280 0.83 ALDH1A1 (0.60) ALDH1A1KMT2APTK2BMCL1MAOB
SCHEMBL29032384 0.81 PARP15 (0.48) ALDH1A1KMT2APTK2BMCL1MAOB
SCHEMBL21924233 0.81 MAOB (0.60) ALDH1A1KMT2APTK2BMCL1MAOB
SCHEMBL31196826 0.79 ESR1 (0.51) ALDH1A1KMT2APTK2BESR1ESR2
SCHEMBL6933452 0.79 ESR1 (0.51) ALDH1A1KMT2APTK2BESR1ESR2
SCHEMBL19225762 0.78 KDM4E (0.51) KMT2AKDM4EL3MBTL1MEN1SMN1; SMN2
SCHEMBL5193644 0.78 NPC1 (0.54) ALDH1A1KMT2APTK2BMCL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119233964-A Single component delivery system for nucleic acids 宾夕法尼亚大学理事会 2024-12-31 CN disclosed