Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | AOC1 | P19801 | 5/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407243 | 1.00 | SLC6A2 (0.49) | SLC6A2SLC6A4AOC1AOC3CYP2A6 | |
| SCHEMBL30825360 | 0.85 | AOC1 (0.41) | SLC6A2SLC6A4AOC1AOC3CYP2A6 | |
| SCHEMBL2996857 | 0.78 | SLC6A2 (0.48) | SLC6A2SLC6A4AOC1AOC3CYP2A6 | |
| SCHEMBL31407203 | 0.78 | SLC6A2 (0.48) | SLC6A2SLC6A4AOC1AOC3CYP2A6 | |
| SCHEMBL31651759 | 0.77 | — | — | |
| SCHEMBL793614 | 0.77 | — | — | |
| SCHEMBL16196603 | 0.77 | KMT2A (0.48) | PARP1KMT2A | |
| SCHEMBL29192994 | 0.77 | AOC1 (0.38) | SLC6A2SLC6A4AOC1AOC3PARP1 | |
| SCHEMBL12836473 | 0.76 | SLC6A2 (0.54) | SLC6A2SLC6A4AOC1AOC3CYP2A6 | |
| SCHEMBL22961934 | 0.76 | AOC1 (0.43) | SLC6A2SLC6A4AOC1AOC3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |