Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Quercetin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 3/20 | 0.79 |
| ▸ | MEN1 | O00255 | 9/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.79 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.79 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.79 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.79 |
| ▸ | RECQL | P46063 | 5/20 | 0.79 |
| ▸ | XDH | P47989 | 5/20 | 0.79 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.79 |
| ▸ | IPMK | Q8NFU5 | 5/20 | 0.79 |
| ▸ | IP6K2 | Q9UHH9 | 5/20 | 0.79 |
| ▸ | APP | P05067 | 5/20 | 0.79 |
| ▸ | POLH | Q9Y253 | 5/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quercetin SCHEMBL29037564 | 1.00 | MEN1 (0.79) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL10860052 | 1.00 | MEN1 (0.79) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL21240733 | 0.91 | MEN1 (0.79) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL3958393 | 0.90 | MEN1 (0.87) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL4173190 | 0.90 | MEN1 (0.87) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL29037553 | 0.89 | MEN1 (0.72) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL31507620 | 0.89 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL17629824 | 0.89 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL19723 | 0.89 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 | |
| Quercetin SCHEMBL118425 | 0.89 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038371-A1 | SALT-LOADED SOLID LIPID NANOPARTICLES LOADED WITH AN ACTIVE AGENT | PURDUE RESEARCH FOUNDATION (US) | 2025-02-20 | — | — | WO | disclosed |