Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408247 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9AMTNR1AMTNR1BPTGES | |
| SCHEMBL31408469 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9AMTNR1AMTNR1BPTGES | |
| SCHEMBL31408388 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9AMTNR1AMTNR1BPTGES | |
| SCHEMBL31408337 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9AMTNR1AMTNR1BPTGES | |
| SCHEMBL31408428 | 0.87 | MAP4K1 (0.35) | SMN1; SMN2MAP4K1 | |
| SCHEMBL31408407 | 0.87 | MAP4K1 (0.35) | SMN1; SMN2MAP4K1 | |
| SCHEMBL31408609 | 0.87 | MAP4K1 (0.35) | SMN1; SMN2MAP4K1 | |
| SCHEMBL31408366 | 0.87 | RAB9A (0.38) | SMN1; SMN2RAB9AMTNR1AMTNR1BPTGES | |
| SCHEMBL31408547 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2RAB9AMTNR1AMTNR1BPTGES | |
| SCHEMBL31408230 | 0.85 | RAB9A (0.38) | SMN1; SMN2RAB9AMTNR1AMTNR1BPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |