Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408457 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2PTGESMAPTLOXL2PRKAG1 | |
| SCHEMBL31408575 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2PTGESMAPTLOXL2PRKAG1 | |
| SCHEMBL31408481 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGESMAPTLOXL2PRKAG1 | |
| SCHEMBL31408480 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGESMAPTLOXL2PRKAG1 | |
| SCHEMBL31408438 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2PTGESMAPTLOXL2PRKAG1 | |
| SCHEMBL31408413 | 0.89 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTLOXL2MTNR1AMTNR1B | |
| SCHEMBL31408525 | 0.89 | MAPK1 (0.39) | SMN1; SMN2PTGESKCNH2SCN5ASCN9A | |
| SCHEMBL31408478 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGESMAPTLOXL2PRKAG1 | |
| SCHEMBL31408262 | 0.88 | MTNR1A (0.43) | SMN1; SMN2PTGESLOXL2MTNR1AMTNR1B | |
| SCHEMBL31408624 | 0.88 | SMN1; SMN2 (0.40) | SMN1; SMN2PTGESMAPTLOXL2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |