Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 7/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | AKT2 | P31751 | 4/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31408419 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2PTGESLOXL2BACE1METTL3 | |
| SCHEMBL31408232 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2PTGESLOXL2METTL3METTL14 | |
| SCHEMBL31408551 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2PTGESLOXL2METTL3METTL14 | |
| SCHEMBL31408542 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2PTGESLOXL2BACE1METTL3 | |
| SCHEMBL31408598 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2PTGESLOXL2BACE1METTL3 | |
| SCHEMBL31408599 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2PTGESLOXL2BACE1METTL3 | |
| SCHEMBL31408526 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2PTGESBACE1METTL3METTL14 | |
| SCHEMBL31408387 | 0.87 | SMN1; SMN2 (0.36) | SMN1; SMN2PTGESBACE1METTL3METTL14 | |
| SCHEMBL31408438 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2PTGESLOXL2PRKAG1PRKAA1 | |
| SCHEMBL31408301 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2PTGESLOXL2PRKAG1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049604-A1 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |