SCHEMBL3140857

SCHEMBL3140857

CCCCCCCCCCCCNc1nc(N(CCCCCCCC)C2CC(C)(C)N(C)C(C)(C)C2)nc(N(CCCCCCCC)C2CC(C)(C)N(C)C(C)(C)C2)n1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.38
TYRO3 Q06418 1/20 0.38
MERTK Q12866 1/20 0.38
GAS6 Q14393 1/20 0.38
DNM2 P50570 9/20 0.36
KMT2A Q03164 1/20 0.35
EHMT2 Q96KQ7 3/20 0.33
EHMT1 Q9H9B1 3/20 0.33
KCNH3 Q9ULD8 2/20 0.33
CAMK2D Q13557 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13415275 1.00 FLT3 (0.38) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415274 1.00 FLT3 (0.38) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415270 0.98 FLT3 (0.38) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415273 0.98 FLT3 (0.38) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415266 0.98 FLT3 (0.38) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL9373111 0.96 FLT3 (0.38) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415268 0.94 FLT3 (0.36) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415263 0.93 FLT3 (0.35) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415259 0.93 FLT3 (0.35) FLT3TYRO3MERTKGAS6DNM2
SCHEMBL13415265 0.93 FLT3 (0.35) FLT3TYRO3MERTKGAS6DNM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION MITSUI CHEMICALS, INC. (JP) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100074083-A1 RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION SEM1, WDR5, WDR1 FLT3 2295/4885TYRO3 2394/4885MERTK 2018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.