SCHEMBL31408779

SCHEMBL31408779

CC(C)(C)OC(=O)Nc1ccc(N)cc1B(O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.39
AAK1 Q2M2I8 5/20 0.38
CYP17A1 P05093 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
MAP4K4 O95819 1/20 0.38
MAPT P10636 2/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.37
KCNQ4 P56696 1/20 0.37
KCNQ5 Q9NR82 1/20 0.37
BRD9 Q9H8M2 1/20 0.36
CISD2 Q8N5K1 1/20 0.36
PIK3CD O00329 1/20 0.36
ABL1 P00519 1/20 0.36
EGFR P00533 1/20 0.36
KDR P35968 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CG P48736 1/20 0.36
BACE1 P56817 1/20 0.36
PRKDC P78527 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3781384 0.84 CA12 (0.47) CYP17A1RXFP1MAP4K4GAABACE1
SCHEMBL15160030 0.83 GAA (0.52) NR1H2AAK1CYP17A1RXFP1MAP4K4
SCHEMBL29951306 0.82 KCNQ4 (0.46) CYP17A1RXFP1GAAKCNQ4KCNQ5
SCHEMBL22535137 0.82 MEN1 (0.51) AAK1CYP17A1MAPT
SCHEMBL1322145 0.82 MAPT (0.54) AAK1CYP17A1MAPTBRD9CISD2
SCHEMBL19935638 0.82 KCNQ4 (0.40) NR1H2AAK1CYP17A1RXFP1MAP4K4
SCHEMBL31604225 0.82 GAA (0.39) NR1H2AAK1CYP17A1RXFP1MAP4K4
SCHEMBL8574647 0.81 NR1I2 (0.42) MAPTCYP1A2
SCHEMBL13283864 0.81 MAPT (0.40) NR1H2AAK1CYP17A1RXFP1MAP4K4
SCHEMBL22113056 0.81 KCNQ4 (0.40) NR1H2AAK1CYP17A1RXFP1MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504808-A Compound, preparation method and application thereof 四川科伦药物研究院有限公司 2025-02-25 CN disclosed