Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ4 | P56696 | 3/20 | 0.46 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781384 | 0.84 | CA12 (0.47) | CYP17A1RXFP1GAA | |
| SCHEMBL857284 | 0.83 | HTT (0.55) | KCNQ4KCNQ5CYP17A1HTTLMNA | |
| SCHEMBL29954656 | 0.82 | KCNQ4 (0.46) | KCNQ4KCNQ5CYP17A1RXFP1HTT | |
| SCHEMBL31408779 | 0.82 | NR1H2 (0.39) | KCNQ4KCNQ5CYP17A1RXFP1BRD9 | |
| SCHEMBL5800267 | 0.82 | KCNQ4 (0.51) | KCNQ4KCNQ5CYP17A1RXFP1HTT | |
| SCHEMBL8292291 | 0.82 | KCNQ4 (0.48) | KCNQ4KCNQ5CYP17A1HTTLMNA | |
| SCHEMBL8574647 | 0.81 | NR1I2 (0.42) | POLB | |
| SCHEMBL22092641 | 0.81 | KCNQ4 (0.47) | KCNQ4KCNQ5CYP17A1RXFP1HTT | |
| SCHEMBL197145 | 0.81 | HDAC1 (0.55) | KCNQ4KCNQ5CYP17A1HTT | |
| SCHEMBL29581478 | 0.81 | HDAC1 (0.55) | KCNQ4KCNQ5CYP17A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |