SCHEMBL31409368

SCHEMBL31409368

[2H]C([2H])([2H])c1cc(Br)cc(C([2H])([2H])[2H])c1NC(=O)CC(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.52
KCNQ2 O43526 11/20 0.46
ALDH1A1 P00352 3/20 0.42
KCNQ3 O43525 1/20 0.42
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOB P27338 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751185 0.89 L3MBTL1 (0.65) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL31441343 0.86 L3MBTL1 (0.55) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL30795680 0.79 L3MBTL1 (0.57) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL1001108 0.79 L3MBTL1 (0.78) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL3112925 0.79 L3MBTL1 (0.57) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL31322184 0.79 L3MBTL1 (0.57) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL23177719 0.77 L3MBTL1 (0.55) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL1000098 0.77 L3MBTL1 (0.55) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL25290879 0.76 L3MBTL1 (0.53) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD
SCHEMBL1001320 0.75 L3MBTL1 (0.49) L3MBTL1KCNQ2ALDH1A1KCNQ3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055343-A Deuterium and aryl amine compounds and uses thereof 泽农医药公司 2026-05-15 CN disclosed
WO-2025064502-A1 DEUTERIUM AND ARYL AMINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS INC. (CA) 2025-03-27 WO disclosed
WO-2025038920-A1 HETEROARYL AMINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS, INC. (CA) 2025-02-20 WO disclosed
WO-2025038917-A1 HETEROARYL AMINE COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS INC. (CA) 2025-02-20 WO disclosed