Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740910 | 0.87 | MAPT (0.44) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL31409400 | 0.84 | MAPT (0.44) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL16217179 | 0.82 | MAPT (0.46) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL29222075 | 0.79 | MAPT (0.43) | ADORA1MAPTESR2NR1H2SMN1; SMN2 | |
| SCHEMBL17327923 | 0.78 | MAPT (0.45) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL31409414 | 0.78 | MAPT (0.45) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL16220569 | 0.78 | MAPT (0.45) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL31409387 | 0.76 | HDAC4 (0.43) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL743031 | 0.76 | MAPT (0.43) | ADORA1MAPTESR2NR1H2MTOR | |
| SCHEMBL156126 | 0.76 | NR1H2 (0.41) | MAPTNR1H2MTORSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038920-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038917-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |