Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | SOD3 | P08294 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779930 | 0.90 | PDCD1 (0.41) | PDCD1CD274PLATADRB1SOD3 | |
| SCHEMBL20027021 | 0.84 | PDCD1 (0.36) | PDCD1CD274SOD3CXCR4 | |
| SCHEMBL16814033 | 0.75 | PDCD1 (0.42) | PDCD1CD274SOD3HTR2AHTR2C | |
| SCHEMBL31460011 | 0.75 | PDCD1 (0.36) | PDCD1CD274SOD3HTR2AHTR2C | |
| SCHEMBL20461181 | 0.75 | PDCD1 (0.36) | PDCD1CD274SOD3HTR2AHTR2C | |
| SCHEMBL31409376 | 0.74 | ADRB1 (0.35) | PLATADRB1ADRB2HTR2CHTR2B | |
| SCHEMBL15456362 | 0.73 | ADRB1 (0.33) | PLATADRB1ADRB2HTR2CHTR2B | |
| SCHEMBL13424015 | 0.73 | PDCD1 (0.44) | PDCD1CD274SOD3HTR2AHTR2C | |
| SCHEMBL30793634 | 0.72 | PDCD1 (0.32) | PDCD1CD274 | |
| SCHEMBL24536069 | 0.71 | PDCD1 (0.36) | PDCD1CD274SOD3CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038920-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038917-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |