Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224995 | 0.89 | ESR2 (0.46) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL31387247 | 0.77 | ESR2 (0.53) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL16217179 | 0.76 | MAPT (0.46) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL29222075 | 0.75 | MAPT (0.43) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL16220569 | 0.75 | MAPT (0.45) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL17327923 | 0.75 | MAPT (0.45) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL31409414 | 0.75 | MAPT (0.45) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL5542914 | 0.74 | ESR2 (0.56) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL31409400 | 0.74 | MAPT (0.44) | MAPTESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL741598 | 0.73 | MAPK1 (0.58) | MAPTESR2NR1H2GRAMD1AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038920-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |
| WO-2025038917-A1 | HETEROARYL AMINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-02-20 | — | — | WO | disclosed |