Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22727565 | 0.78 | C5AR1 (0.44) | ESR2NR1H2MAPTMAPK1GRAMD1A | |
| SCHEMBL2132733 | 0.78 | ESR2 (0.53) | ESR2NR1H2MAPTMAPK1GRAMD1A | |
| SCHEMBL31301219 | 0.77 | NAMPT (0.46) | MAPTUSP2SMN1; SMN2NAMPT | |
| SCHEMBL16217165 | 0.77 | MAPT (0.54) | ESR2NR1H2MAPTMAPK1GRAMD1A | |
| SCHEMBL31409404 | 0.77 | MAPT (0.48) | ESR2NR1H2MAPTMAPK1GRAMD1A | |
| SCHEMBL22716642 | 0.76 | C5AR1 (0.43) | ESR2NR1H2MAPTMAPK1GRAMD1A | |
| SCHEMBL29640130 | 0.76 | NAMPT (0.46) | MAPTNAMPT | |
| SCHEMBL25085668 | 0.76 | ESR2 (0.57) | ESR2NR1H2MAPTMAPK1GRAMD1A | |
| SCHEMBL16379671 | 0.76 | MAPT (0.53) | ESR2NR1H2MAPTMAPK1GRAMD1A | |
| SCHEMBL1620629 | 0.76 | MAPT (0.58) | ESR2NR1H2MAPTMAPK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024255765-A1 | NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF | NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) | 2024-12-19 | — | — | WO | disclosed |