Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26930227 | 0.80 | USP30 (0.40) | USP30POLBAAK1LIPEPRMT5 | |
| SCHEMBL30674343 | 0.80 | USP30 (0.40) | USP30POLBAAK1LIPEPRMT5 | |
| SCHEMBL23089644 | 0.79 | USP30 (0.38) | USP30POLBAAK1L3MBTL1BUB1 | |
| SCHEMBL29814546 | 0.79 | USP30 (0.38) | USP30POLBAAK1L3MBTL1BUB1 | |
| SCHEMBL29736431 | 0.78 | PIM1 (0.37) | USP30PRMT5WDR77L3MBTL1BUB1 | |
| SCHEMBL23089111 | 0.78 | PIM1 (0.37) | USP30PRMT5WDR77L3MBTL1BUB1 | |
| SCHEMBL23089278 | 0.78 | USP30 (0.37) | USP30AAK1LIPEPRMT5WDR77 | |
| SCHEMBL29736467 | 0.78 | USP30 (0.37) | USP30AAK1LIPEPRMT5WDR77 | |
| SCHEMBL31409645 | 0.77 | POLB (0.42) | POLBATRL3MBTL1BUB1BRD4 | |
| SCHEMBL31409613 | 0.77 | POLB (0.42) | USP30POLBATRL3MBTL1BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |