Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.32 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409645 | 0.85 | POLB (0.42) | POLBATRL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL31164375 | 0.78 | GABRG2 (0.33) | POLBATRL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL31409565 | 0.77 | USP30 (0.38) | POLBATRL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL15695740 | 0.75 | POLB (0.44) | POLBATRL3MBTL1HSP90AA1HSP90AB1 | |
| SCHEMBL3248285 | 0.75 | L3MBTL1 (0.43) | POLBL3MBTL1HTR6PIK3R1PIK3CA | |
| SCHEMBL23748055 | 0.75 | L3MBTL1 (0.45) | L3MBTL1HTR6PIK3R1PIK3CABCHE | |
| SCHEMBL30548022 | 0.75 | L3MBTL1 (0.45) | L3MBTL1HTR6PIK3R1PIK3CABCHE | |
| SCHEMBL1710746 | 0.74 | PIM1 (0.42) | L3MBTL1HTR6BCHEMEN1KMT2A | |
| SCHEMBL23300758 | 0.74 | L3MBTL1 (0.42) | L3MBTL1HTR6BCHEMEN1KMT2A | |
| SCHEMBL20508874 | 0.73 | L3MBTL1 (0.36) | POLBL3MBTL1HSP90AA1HSP90AB1PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |