Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 14/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24434982 | 0.86 | AOC3 (0.53) | AOC3MAOBSIRT1LMNA | |
| SCHEMBL944485 | 0.80 | PI4KB (0.51) | AOC3HDAC1SIRT1LMNA | |
| SCHEMBL12742401 | 0.80 | PTPRB (0.49) | AOC3HDAC1SIRT1LMNA | |
| SCHEMBL6495932 | 0.78 | AOC3 (0.54) | AOC3HDAC1HDAC6MAOBSIRT1 | |
| SCHEMBL2668827 | 0.78 | SIRT1 (0.48) | AOC3HDAC1SIRT1LMNA | |
| SCHEMBL13033265 | 0.78 | SIRT1 (0.49) | HDAC1SIRT1LMNA | |
| SCHEMBL972059 | 0.78 | AOC3 (0.60) | AOC3MAOBLMNA | |
| SCHEMBL973715 | 0.78 | AOC3 (0.60) | AOC3MAOBLMNA | |
| SCHEMBL972993 | 0.78 | AOC3 (0.60) | AOC3MAOBLMNA | |
| SCHEMBL1030124 | 0.77 | PI4KB (0.50) | HDAC1SIRT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025026997-A1 | SUBSTITUED BICYCLIC HETEROCYCLIC YAP-TEAD AND/OR TAZ-TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2025-02-06 | — | — | WO | disclosed |