Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.57 |
| ▸ | MDM4 | O15151 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | TNF | P01375 | 3/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632223 | 1.00 | CASP3 (0.57) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL6190530 | 1.00 | CASP3 (0.57) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL29508216 | 1.00 | CASP3 (0.57) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL119370 | 1.00 | CASP3 (0.57) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL31681818 | 1.00 | CASP3 (0.57) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL29379911 | 1.00 | CASP3 (0.57) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL30656568 | 0.93 | MDM4 (0.59) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL8009538 | 0.91 | CASP3 (0.53) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL29613683 | 0.91 | CASP3 (0.55) | CASP3MDM4TP53TNFMDM2 | |
| SCHEMBL29277316 | 0.90 | CASP3 (0.54) | CASP3MDM4TP53TNFMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076219-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |