Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LPO | P22079 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083384 | 0.75 | KMT2A (0.50) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL8283637 | 0.70 | KMT2A (0.45) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL28784054 | 0.70 | KMT2A (0.45) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL12928752 | 0.68 | KMT2A (0.46) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL8415398 | 0.67 | KMT2A (0.56) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL11050545 | 0.67 | KMT2A (0.56) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL29393799 | 0.67 | KMT2A (0.45) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL22863264 | 0.66 | KMT2A (0.50) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL419709 | 0.66 | KMT2A (0.50) | KMT2ATSHRFDPSPKMMAPK1 | |
| SCHEMBL23367672 | 0.66 | KMT2A (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076219-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |