Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083384 | 0.85 | KMT2A (0.50) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL8283637 | 0.83 | KMT2A (0.45) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL1046397 | 0.76 | KMT2A (0.40) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL8415398 | 0.75 | KMT2A (0.56) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL11050545 | 0.75 | KMT2A (0.56) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL22863264 | 0.74 | KMT2A (0.50) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL419709 | 0.74 | KMT2A (0.50) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL28839172 | 0.74 | KMT2A (0.41) | KMT2ALPOTSHRFDPSALDH1A1 | |
| Hydrochloric Acid SCHEMBL16540240 | 0.73 | KMT2A (0.48) | KMT2ALPOTSHRFDPSALDH1A1 | |
| SCHEMBL28784054 | 0.72 | KMT2A (0.45) | KMT2ALPOTSHRFDPSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868036-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-01-11 | — | — | US | disclosed |
| US-20080058320-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-03-06 | — | — | US | disclosed |
| US-20070066582-A1 | Diaminoalcohols as therapeutic compounds | SPEEDEL EXPERIMENTA AG (CH) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066582-A1 | Diaminoalcohols as therapeutic compounds | CTSD, CTSL, CTSC | KMT2A 3003/4885LPO 2651/4885TSHR 3964/4885 |
| US-20080058320-A1 | Organic Compounds | REN, AGTR1, ADH1C | KMT2A 3647/4885LPO 491/4885TSHR 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.