Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.46 |
| ▸ | NPY1R | P25929 | 7/20 | 0.46 |
| ▸ | NPY2R | P49146 | 5/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | TFPI | P10646 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297059 | 0.91 | IL23R (0.42) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL31410639 | 0.90 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL31303214 | 0.90 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL11833339 | 0.90 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5RTFPI | |
| SCHEMBL31410680 | 0.90 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL30124571 | 0.89 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RTFPI | |
| SCHEMBL30208666 | 0.89 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RTFPI | |
| SCHEMBL8062296 | 0.89 | KEAP1 (0.45) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL8062301 | 0.89 | KEAP1 (0.45) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL31343200 | 0.89 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5RKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462820-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Gly-Gly as well as preparation and application thereof | 首都医科大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-119390755-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Val-Val, preparation and application thereof | 首都医科大学 | 2025-02-07 | — | — | CN | disclosed |