Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405300 | 0.88 | KMT2A (0.40) | KMT2ATP53MEN1HSD17B10HTT | |
| SCHEMBL30454138 | 0.83 | KMT2A (0.38) | KMT2ATP53MEN1HSD17B10HTT | |
| SCHEMBL31405272 | 0.83 | KMT2A (0.38) | KMT2ATP53MEN1HSD17B10HTT | |
| SCHEMBL22073032 | 0.81 | TDP1 (0.59) | KMT2ATP53MEN1HTTMAPT | |
| SCHEMBL30631846 | 0.81 | TDP1 (0.59) | KMT2ATP53MEN1HTTMAPT | |
| SCHEMBL31405311 | 0.81 | KMT2A (0.38) | KMT2ATP53MEN1HSD17B10HTT | |
| SCHEMBL29196758 | 0.81 | TDP1 (0.41) | KMT2ATP53MEN1HSD17B10HTT | |
| SCHEMBL31411226 | 0.79 | KDR (0.37) | KMT2ATP53MEN1HSD17B10HTT | |
| SCHEMBL31405301 | 0.78 | RPS6KB1 (0.42) | KMT2ATP53MEN1HSD17B10HTT | |
| SCHEMBL31405302 | 0.78 | KMT2A (0.37) | KMT2ATP53MEN1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219601-A | Preparation method of 4- (2, 2-dimethyl-2-cyanoethyl) -beta-lactam derivative | 苏州大学 | 2024-12-31 | — | — | CN | disclosed |