Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MECP2 | P51608 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631846 | 1.00 | TDP1 (0.59) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL30500763 | 0.87 | TDP1 (0.62) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL22072296 | 0.87 | TDP1 (0.62) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL30631849 | 0.86 | POLB (0.55) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL29152858 | 0.82 | SLC40A1 (0.70) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL22073021 | 0.81 | POLB (0.58) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL30631865 | 0.81 | POLB (0.58) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL30434501 | 0.81 | TDP1 (0.58) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL28601254 | 0.81 | TDP1 (0.58) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL31411228 | 0.81 | KMT2A (0.39) | TDP1POLBMAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117126135-A | Synthesis method of 3, 4-diaminobutyric acid derivative | 常州大学 | 2023-11-28 | — | — | CN | disclosed |
| US-20210276986-A1 | METHOD FOR PREPARING BETA-LACTAM DERIVATIVE | SOOCHOW UNIVERSITY (CN) | 2021-09-09 | — | — | US | disclosed |
| WO-2020114025-A1 | PREPARATION METHOD FOR β-LACTAM DERIVATIVES | 苏州大学 | 2020-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276986-A1 | METHOD FOR PREPARING BETA-LACTAM DERIVATIVE | TBCB, QDPR, UBE2B | TDP1 2769/4885POLB 249/4885MAPT 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.