SCHEMBL31411273

SCHEMBL31411273

CC(C)N(C)CCc1nn(C2CCCCO2)c2ccc(F)c(F)c12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RET P07949 2/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
BRAF P15056 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411438 0.91 CYP4F2 (0.34) RETCYP4F2CYP4A11RXRARXRB
SCHEMBL31411465 0.88 CYP4F2 (0.33) RETCYP4F2CYP4A11RXRARXRB
SCHEMBL31411328 0.83 CYP4F2 (0.38) RETCYP4F2CYP4A11RXRARXRB
SCHEMBL31411393 0.81 CD274 (0.35) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL31411269 0.81 CD274 (0.35) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL31411288 0.79 CYP4F2 (0.38) RETCYP4F2CYP4A11RXRARXRB
SCHEMBL19204904 0.75 CYP4F2 (0.39) RETCYP4F2CYP4A11RXRARXRB
SCHEMBL31411399 0.73 KMT2A (0.39)
SCHEMBL31411442 0.72 CYP4F2 (0.37) RETCYP4F2CYP4A11RXRARXRB
SCHEMBL31105972 0.69 GAA (0.45) RETCYP4F2CYP4A11RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735425-A1 COMPOUNDS Psylo Pty Ltd (AU) 2026-05-06 EP disclosed
US-20250353818-A1 Compounds Psylo Pty Ltd (AU) 2025-11-20 US disclosed
US-12428380-B2 Compounds Psylo Pty Ltd (AU) 2025-09-30 US disclosed
US-20250214943-A1 Compounds Psylo Pty Ltd (AU) 2025-07-03 US disclosed
WO-2025000053-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-01-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214943-A1 Compounds NLN, SLC18A2, PYGB RET 2844/4885CYP4F2 614/4885CYP4A11 1465/4885
US-12428380-B2 Compounds NLN, SLC18A2, PYGB RET 2844/4885CYP4F2 614/4885CYP4A11 1465/4885
US-20250353818-A1 Compounds NLN, SLC18A2, PYGB RET 2844/4885CYP4F2 614/4885CYP4A11 1465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.