Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1265834 | 0.98 | PARP1 (0.60) | PARP1MAPTS1PR1KDM4EALDH1A1 | |
| SCHEMBL1265563 | 0.83 | MAPT (0.57) | PARP1MAPTS1PR1KDM4ETDP1 | |
| SCHEMBL29745271 | 0.83 | MAPT (0.57) | PARP1MAPTS1PR1KDM4ETDP1 | |
| SCHEMBL762009 | 0.79 | MAPT (0.42) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL6750187 | 0.76 | MAPT (0.40) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL7185293 | 0.76 | MAPT (0.53) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL21441148 | 0.75 | MAPT (0.47) | PARP1MAPTS1PR1KDM4EALDH1A1 | |
| SCHEMBL15979923 | 0.75 | CTNNB1 (0.56) | PARP1MAPTP2RY14 | |
| SCHEMBL4619270 | 0.74 | PARP1 (1.00) | PARP1ALDH1A1 | |
| SCHEMBL29966835 | 0.74 | PARP1 (1.00) | PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219694-A | Low-dimensional perovskite single crystal, low-dimensional/three-dimensional perovskite thin film, perovskite solar cell and preparation method | 郑州大学 | 2024-12-31 | — | — | CN | disclosed |