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Tyrocidine A1

Tyrocidine A1

SCHEMBL31412201

CC(C)C[C@H]1NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](C(C)C)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HDAC4 P56524 2/20 0.56
▸ CIB1 Q99828 1/20 0.55
▸ TFPI P10646 4/20 0.55
▸ PLG P00747 1/20 0.53
▸ ITGB3 P05106 1/20 0.53
▸ ITGB1 P05556 1/20 0.53
▸ ITGAV P06756 1/20 0.53
▸ ITGA5 P08648 1/20 0.53
▸ ITGB5 P18084 1/20 0.53
▸ FLT1 P17948 1/20 0.53
▸ PCSK9 Q8NBP7 1/20 0.52
▸ ALB P02768 1/20 0.52
▸ KLK5 Q9Y337 1/20 0.52
▸ NTSR1 P30989 4/20 0.52
▸ PDCD1 Q15116 1/20 0.51
▸ CD274 Q9NZQ7 1/20 0.51
▸ ELANE P08246 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrocidine A1 SCHEMBL29489412 1.00 HDAC4 (0.56) HDAC4CIB1TFPIPLGITGB3
Tyrocidine A SCHEMBL14399288 0.98 HDAC4 (0.55) HDAC4CIB1TFPIPLGITGB3
Tyrocidine A SCHEMBL12131172 0.98 HDAC4 (0.55) HDAC4CIB1TFPIPLGITGB3
Tyrocidine A SCHEMBL16418974 0.98 HDAC4 (0.55) HDAC4CIB1TFPIPLGITGB3
SCHEMBL17133082 0.95 FLT1 (0.57) HDAC4CIB1TFPIPLGITGB3
Laterocidin SCHEMBL29824961 0.94 FLT1 (0.56) HDAC4TFPIPLGITGB3ITGB1
Loloatin A SCHEMBL6050533 0.94 FLT1 (0.56) HDAC4TFPIPLGITGB3ITGB1
SCHEMBL31412206 0.93 TFPI (0.50) HDAC4CIB1TFPIPLGITGB3
Tyrocidine B1 SCHEMBL29489417 0.93 PDCD1 (0.62) HDAC4CIB1FLT1PCSK9PDCD1
Tyrocidine C1 SCHEMBL29489410 0.93 PDCD1 (0.62) HDAC4CIB1FLT1PCSK9PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390779-B Antibacterial cyclic peptide and application thereof 浙江大学 2025-10-28 — — CN disclosed
CN-119390779-A Antibacterial cyclic peptide and application thereof 浙江大学 2025-02-07 — — CN disclosed
CN-119390779-A Antibacterial cyclic peptide and application thereof 浙江大学 2025-02-07 — — CN disclosed