Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.56 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.55 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.54 |
| ▸ | TCF4 | P15884 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | TFPI | P10646 | 4/20 | 0.52 |
| ▸ | GRB2 | P62993 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Laterocidin SCHEMBL29824961 | 1.00 | FLT1 (0.56) | FLT1PLGITGB3ITGB1ITGAV | |
| SCHEMBL17133082 | 0.96 | FLT1 (0.57) | FLT1PLGITGB3ITGB1ITGAV | |
| Tyrocidine A SCHEMBL12131172 | 0.95 | HDAC4 (0.55) | FLT1PLGITGB3ITGB1ITGAV | |
| Tyrocidine A SCHEMBL16418974 | 0.95 | HDAC4 (0.55) | FLT1PLGITGB3ITGB1ITGAV | |
| Tyrocidine A SCHEMBL14399288 | 0.95 | HDAC4 (0.55) | FLT1PLGITGB3ITGB1ITGAV | |
| Tyrocidine A1 SCHEMBL31412201 | 0.94 | HDAC4 (0.56) | FLT1PLGITGB3ITGB1ITGAV | |
| Tyrocidine A1 SCHEMBL29489412 | 0.94 | HDAC4 (0.56) | FLT1PLGITGB3ITGB1ITGAV | |
| Gratisin SCHEMBL29885076 | 0.93 | HDAC4 (0.58) | FLT1PLGITGB3ITGB1ITGAV | |
| Loloatin B SCHEMBL1231277 | 0.92 | PDCD1 (0.66) | FLT1PDCD1CD274PCSK9HDAC4 | |
| Loloatin C SCHEMBL6050512 | 0.92 | PDCD1 (0.66) | FLT1PDCD1CD274PCSK9HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153826-B2 | Treatment of rosacea | SEATEK MARINE BIOTECHNOLOGY, INC. (CA) | 2006-12-26 | — | — | US | claimed |
| US-20040023857-A1 | Treatment of rosacea | SEATEK MARINE BIOTECHNOLOGY INC. (CA) | 2004-02-05 | — | — | US | claimed |
| WO-2001068675-A2 | TREATMENT OF ROSACEA | SEATEK MARINE BIOTECHNOLOGY INC. (CA) | 2001-09-20 | — | — | WO | claimed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| CN-109354604-A | A kind of linear false polypeptide and preparation method thereof and purposes | 广州药本君安医药科技股份有限公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-109021068-A | A kind of linear false polypeptide and preparation method thereof and the application in antibacterials | 暨南大学 | 2018-12-18 | — | — | CN | disclosed |
| CN-108864253-A | A kind of linear false polypeptide and preparation method thereof and its application in anti-tumor drug | 暨南大学 | 2018-11-23 | — | — | CN | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| CN-101906138-B | Pseudo cyclic polypeptide and synthesis method and application thereof | UNIV JINAN | 2012-10-17 | — | — | CN | disclosed |
| CN-101906138-A | Pseudo cyclic polypeptide and synthesis method and application thereof | UNIV JINAN | 2010-12-08 | — | — | CN | disclosed |
| CN-101906149-A | Linear polypeptide and synthetic method and application thereof | UNIV JINAN | 2010-12-08 | — | — | CN | disclosed |
| US-7153826-B2 | Treatment of rosacea | SEATEK MARINE BIOTECHNOLOGY, INC. (CA) | 2006-12-26 | — | — | US | disclosed |
| US-6790829-B1 | Cyclic decapeptide antibiotics | SEATEK MARINE BIOTECHNOLOGY, INC. (CA) | 2004-09-14 | — | — | US | disclosed |
| US-20040023857-A1 | Treatment of rosacea | SEATEK MARINE BIOTECHNOLOGY INC. (CA) | 2004-02-05 | — | — | US | disclosed |
| WO-2001068675-A2 | TREATMENT OF ROSACEA | SEATEK MARINE BIOTECHNOLOGY INC. (CA) | 2001-09-20 | — | — | WO | disclosed |
| US-5962407-A | CYCLIC DECAPEPTIDES ARE ACTIVE AGAINST BOTH GRAM POSITIVE AND GRAM NEGATIVE BACTERIA. | SEATEK MARINE BIOTECHNOLOGY, INC. | 1999-10-05 | — | — | US | disclosed |
| WO-1998004584-A1 | CYCLIC DECAPEPTIDE ANTIBIOTICS | SEATEK MARINE BIOTECHNOLOGY, INC. (CA) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023857-A1 | Treatment of rosacea | RXFP1, LPXN, LRPPRC | FLT1 94/4885PLG 1235/4885ITGB3 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.