⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31491019 | 0.84 | — | — | |
| SCHEMBL30699763 | 0.81 | — | — | |
| SCHEMBL31406530 | 0.80 | — | — | |
| SCHEMBL31412211 | 0.78 | MAPT (0.38) | — | |
| SCHEMBL30699839 | 0.78 | — | — | |
| SCHEMBL22029150 | 0.76 | — | — | |
| SCHEMBL29937105 | 0.76 | — | — | |
| SCHEMBL27053778 | 0.74 | EPRS1 (0.32) | — | |
| SCHEMBL27053763 | 0.74 | — | — | |
| SCHEMBL24820532 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591588-A | RAS inhibitors | 泰励生物科技（上海）有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2025049274-A2 | TETRACYCLIC DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |