Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 3/20 | 0.42 |
| ▸ | GABRD | O14764 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28879374 | 0.85 | HSP90AA1 (0.73) | HSP90AA1KDM4ENAPRTHCAR2ADORA3 | |
| Carbamic Acid SCHEMBL620105 | 0.85 | HSP90AA1 (0.73) | HSP90AA1KDM4ENAPRTHCAR2ADORA3 | |
| Acetic Acid SCHEMBL20764763 | 0.83 | HSP90AA1 (0.70) | HSP90AA1KDM4ENAPRTHCAR2ADORA3 | |
| Urea SCHEMBL27588147 | 0.83 | HSP90AA1 (0.76) | HSP90AA1KDM4ENAPRTHCAR2ADORA3 | |
| Acetone SCHEMBL28643067 | 0.81 | HSP90AA1 (0.73) | HSP90AA1KDM4ENAPRTHCAR2ADORA3 | |
| Benzene SCHEMBL27818129 | 0.80 | HSP90AA1 (0.89) | HSP90AA1KDM4ENAPRTHCAR2ADORA3 | |
| SCHEMBL29032 | 0.80 | — | — | |
| SCHEMBL30029374 | 0.80 | — | — | |
| SCHEMBL10426450 | 0.80 | — | — | |
| Acetamide SCHEMBL28820773 | 0.79 | HSP90AA1 (0.70) | HSP90AA1KDM4ENAPRTHCAR2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798173-A | Series 2-aminopyrazinyl salt birefringent optical crystal, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-04-11 | — | — | CN | claimed |
| CN-119798173-A | Series 2-aminopyrazinyl salt birefringent optical crystal, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-04-11 | — | — | CN | disclosed |
| CN-119798173-A | Series 2-aminopyrazinyl salt birefringent optical crystal, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2025-04-11 | — | — | CN | disclosed |