Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30474184 | 1.00 | ESR2 (0.56) | ESR2NR1H2GPR119MAP3K5MEN1 | |
| SCHEMBL17221588 | 0.91 | GPR119 (0.49) | ESR2NR1H2GPR119MEN1KMT2A | |
| SCHEMBL5599594 | 0.91 | ESR2 (0.62) | ESR2NR1H2GPR119MEN1KMT2A | |
| SCHEMBL29516101 | 0.86 | NR1H2 (0.61) | ESR2NR1H2GPR119MEN1KMT2A | |
| SCHEMBL19513096 | 0.84 | ESR2 (0.55) | ESR2NR1H2GPR119MAP3K5JAK2 | |
| SCHEMBL23684302 | 0.83 | ESR2 (0.64) | ESR2NR1H2MAP3K5MAPK1MAPT | |
| SCHEMBL30199587 | 0.83 | ESR2 (0.64) | ESR2NR1H2MAP3K5MAPK1MAPT | |
| SCHEMBL21470912 | 0.83 | ESR2 (0.64) | ESR2NR1H2MAP3K5MAPK1MAPT | |
| SCHEMBL30260152 | 0.83 | ESR2 (0.64) | ESR2NR1H2MAP3K5MAPK1MAPT | |
| SCHEMBL4171400 | 0.81 | NR1H2 (0.65) | ESR2NR1H2MAP3K5MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |