Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139933 | 1.00 | HTT (0.48) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL27143488 | 0.86 | ALOX15 (0.44) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL31413422 | 0.86 | ALOX15 (0.44) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL16016025 | 0.84 | NPC1 (0.47) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL16016027 | 0.84 | NPC1 (0.47) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL31413467 | 0.80 | ALOX15 (0.43) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL27143721 | 0.80 | ALOX15 (0.43) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL31413455 | 0.80 | ALOX15 (0.43) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL27138635 | 0.80 | ALOX15 (0.43) | HTTALOX15NPC1RAB9AHSP90AA1 | |
| SCHEMBL31413479 | 0.79 | HTT (0.47) | HTTALOX15NPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119325469-A | WEE1 degrading compounds and uses thereof | 百时美施贵宝公司 | 2025-01-17 | — | — | CN | disclosed |